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pingpongbeast

 
 
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The simplest of enzymes will involve one substrate binding to the enzyme and producing a product plus the enzyme. However, the majority of enzymes are more complex and catalyze reactions involving multiple substrates. Binding of two substrates can occur through two mechanisms: sequential mechanism and non-sequential mechanism. In sequential mechanisms both substrates bind the enzyme and the reaction proceeds to form products which are then released from the enzyme. This mechanism can be further subdivided into random and ordered reactions. For random reactions the order in which the substrates bind does not matter. In ordered reactions one substrate must bind the enzyme before the second substrate is able to bind. Non-Sequential mechanism does not require both substrates to bind before releasing the first product. This page will focus on the non-sequential mechanism, which is also known as the "ping-pong" mechanism.

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